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Weight & metabolic

Tirzepatide

LY3298176
dose range
2.5–15 mg
frequency
1×/wk · subq
cycle
Continuous
half-life
~5 days
vials
10 · 20 · 30 · 40 · 60 mg
recon @ fridge
56 days
Receptor logic
GIP / GLP-1 dual agonist

Dual incretin agonism. GIP component improves the side-effect ceiling vs pure GLP-1, allowing higher effective exposure.

What to watch

Titrate in 2.5 mg steps every 4 weeks. GI tolerance is the rate limiter, not efficacy.

Stacks with

Often the GLP-1 backbone; cycle off-ramps matter to preserve lean mass.

Stability
Lyophilized
Frozen · as-shipped, sealed
12+ months
Reconstituted
Refrigerated · 2–8°C, working state
56 days
Reconstituted
Room · avoid; degrades fast
21 days
Vial sizes · source the peptide
TIRZ-10 · 10mgBuy · Vialogy →
TIRZ-20 · 20mgBuy · Vialogy →
TIRZ-30 · 30mgBuy · Vialogy →
TIRZ-40 · 40mgBuy · Vialogy →
TIRZ-60 · 60mgBuy · Vialogy →
Bacteriostatic water
you'll need this to reconstitute
Water · StatWater →
Orders are saved to your account, so reorder reminders know what you bought.
Citations
Jastreboff 2022 · NEJM · SURMOUNT-1